Prognosis of delirium in hospitalized elderly: worse than we thought
Background
Despite treatment of the associated condition, delirious persons do not always recover for unknown reasons. We sought to determine early prognostic indicators of poor recovery following an episode of delirium in older medical in-patients. Methods
Between October 2009 and…
Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease
Abstract
The pathophysiological process of Alzheimer’s disease (AD) is thought to begin many years before the diagnosis of AD dementia. This long “preclinical” phase of AD would provide a critical opportunity for therapeutic intervention; however, we need to further elucidate…
The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease
Guy M. McKhann, David S. Knopman, Howard Chertkow, Bradley T. Hyman, Clifford R. Jack Jr., Claudia H. Kawash et al.
Abstract
The National Institute on Aging and the Alzheimer’s Association charged a workgroup with the task of revising the 1984…
The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease
Marilyn S. Albert, Steven T. DeKosky, Dennis Dickson, Bruno Dubois, Howard H. Feldman,Nick C. Fox, Anthony Gamst, David M. Holtzman, William J. Jagust, Ronald C. Petersen, Peter J. Snyder, Maria C. Carrillo, Bill Thies, Creighton H. Phelps
Abstract
The National…
Mathematical Difficulties in Nonverbal Learning Disability or Co-Morbid Dyscalculia and Dyslexia
Irene C. Mammarella, Monica Bomba, Sara Caviola, Fiorenza Broggi, Francesca Neri, Daniela Lucangeli & Renata Nacinovich
Abstract : The main goal of the present study was to shed further light on the weaknesses of children with different profiles of…
Does a Third Party Observer Affect Neuropsychological Test Performance? It Depends
Decreased Cognitive Function in Extended Family Members from the Single Late-Onset-Alzheimer’s-Disease Pedigree
http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8956740
Frequency and bases of abnormal performance by healthy adults on neuropsychological testing
The frequency and determinants of abnormal test performance by normal individuals are critically important to clinical inference. Here we compare two approaches to predicting rates of abnormal test performance among healthy individuals with the rates actually shown by 327 neurologically…
Frontal Defects Contribute to the Genesis of Closing-in in Alzheimer’s Disease Patients
Closing-in (CI) refers to copying drawings near to or superimposed on the original model, and is often observed in Alzheimer’s disease (AD) patients. Contrasting hypotheses have been suggested to explain CI, but no prospective study has directly verified these interpretations….
Evolution of mild cognitive impairment in Parkinson disease
Objective: We examined the development of Parkinson disease (PD)–mild cognitive impairment (MCI) in patients with newly diagnosed PD over 5 years using recently proposed consensus criteria, and we assessed the reliability of the criteria.
Methods:…